This project deals with the synthesis of electrospun nanofibrous scaffolds for applications in substrates for biosensors, mammalian cell growth, and scaffolds for tissue engineering. Scaffolds made up of polymers such as PVA, PLA, PGA, PCL, chitosan, and collagen are synthesized and studied for the above applications. Carbon-based nanoparticles such as graphene, carbon nanotubes, and graphene oxide are also introduced within the substrates for application-specific substrates.

Utilize cyclic voltammetry and electrochemical impedance spectroscopy to synthesize and test electropolymerized substrates for electrochemical biosensors.

Study the interactions of the biological macromolecules such as proteins, DNA, and cell membrane with each other and carbon-based nanoparticles. Criteria such as stability and energetics are explored to gain crucial insights about the interface and apply this understanding to applications such as biosensor development and in vivo biophysical phenomena.

Analyze the molecular events at the interface of NDPK and any prospective molecules that may potentially influence its active site.

Elucidate the interactions between human MutS Beta mismatch repair protein and mismatched DNA from the perspectives of stability and energetics of the complex.

Understand the interactions at the interface of bacterial cell surface proteins and the cancer cell surface. This research leverages the chemical properties of magnetotactic bacteria to regulate the apoptosis of cancerous cells.